The Effect of Fibrin Glue on the Intensity of Colonic Anastomosis in the Presence and Absence of Peritonitis: An Experimental Randomized Controlled Trial on Rats

Table 2

The Comparisons of bursting pressure and hydroxyproline levels and histopathological variables and scores within the groups.

Outcome measurements	Clean-glue; (𝑛=10)	Clean-control; (𝑛=10)	𝑃	Peritonitis-glue; (𝑛=10)	Peritonitis-control; (𝑛=9)	𝑃
Bursting pressure (mmHg)	269.5±12.1	232.5±7.9	<0.001	236.5±20.6	201.1±11.9	0.001
Hydroxyproline level; (mcg/gram tissue)	266.2±51.2	196.4±44.5	0.002	148.8±24.6	108.8±21.8	0.001
Histopathological variables and score
Total score	14.6±0.8	13.5±0.7	0.007	11.7±1.2	9.1±1.1	0.001
Inflammatory cell	3.8±0.4	3.4±0.5	0.075	2.2±0.6	2.4±0.5	0.576
Fibroblasts	3.7±0.5	3.4±0.5	0.189	3.1±0.6	2.2±0.4	0.007
Neovascularization	3.7±0.5	3.4±0.5	0.189	3.0±0.7	2.2±0.4	0.027
Collagen	3.4±0.5	3.3±0.5	0.648	3.8±0.5	2.4±0.5	0.004

(Data are presented in mean and standard deviations [±SD]).