Dietary Supplementation of Calendula officinalis Counteracts the Oxidative Stress and Liver Damage Resulted from Aflatoxin

Table 4

Effect of ethanol extract of calendula on serum inflammatory cytokine in rats fed aflatoxins-contaminated diet.

Parameter	Group
	Control	AFs	CE1	CE2	CE1 + AFs	CE2 + AFs
TNF-α (pg/mL)	58.34 ± 3.12^a	131.12 ± 3.32^b	58.37 ± 2.07^a	60.72 ± 1.92^a	86.47 ± 2.31^c	63.24 ± 1.66^d
IL-1β (pg/mL)	0.66 ± 0.07^a	2.34 ± 0.12^b	0.65 ± 0.04^a	0.84 ± 0.22^a	1.58 ± 0.04^c	0.77 ± 0.21^a

Within each row, means superscript with different letters are significantly different at 𝑃 ≤ 0.05.
AFs: aflatoxins.
CE1: low dose of calendula extract (500 mg/kg b.w).
CE2: high dose of calendula extract (1000 mg/kg b.w).