Research Article
Validation of Simultaneous Volumetric and HPLC Methods for the Determination of Pridinol Mesylate in Raw Material
| Condition | Time (h) | % of pridinol mesylate | RRT of degradation products |
| Acid (6 N HCl, reflux) | 0.5 | 9.8 | 0.29, 0.33, 0.4, 0.49, 1.24, 1.88, 2.26 | Base (5 N NaOH, reflux) | 0.5 | 11.5 | 0.23, 0.33 | Hydrogen peroxide 100 vol (reflux) | 0.5
| 68.2
| 0.33, 1.16, 1.6
| Dry heat, 50°C (solid) | 1.5 | 99.5 | 0.35 | Daylight exposure | 96 | 100.4 | Non detected |
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RRT: relative retention time.
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