Research Article

Amelioration of Collagen-Induced Arthritis in Female Dark Agouti Rats by Glucosamine Treatment

Table 1

The histopathological characteristics observed in a joint affected by rheumatoid arthritis and the grading system for the analysis of joints.

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OedemaNil Mild Moderate Severe
Cellular Infiltration Nil Mild scattered infiltration Lymphocytes and macrophages Sheets of inflammatory cells/granulomas/MNG cells
Joint space No narrowing Mild narrowing Moderate narrowing with very little intermeningeal space Total obliteration of joint space
Synovial hyperplasia Nil Mild Moderate Extensive
Fibrosis Nil Mild Moderate Extensive/severe
Erosion Absent Present