Table of Contents
ISRN Nephrology
Volume 2013, Article ID 573735, 4 pages
Clinical Study

Incidence of Renal Involvement in Malaria in Children of Odisha

1Department of Pediatrics, Kalinga Institute of Medical Sciences, KIIT Campus-5, Patia, Odisha, Bhubaneswar 751024, India
2Department of Physiology, Kalinga Institute of Medical Sciences, KIIT Campus-5, Patia, Odisha, Bhubaneswar 751024, India

Received 25 August 2012; Accepted 24 September 2012

Academic Editors: P. Cravedi and A. Tzamaloukas

Copyright © 2013 Rajesh Kumar Padhi and Soumya Mishra. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


About 500 million people suffer from malaria leading to death in 2-3 million cases every year, of which about 1 million are children. Horstman et al., 1985, and Weber et al., 1991, demonstrated an acute renal failure as a well-described complication of Plasmodium falciparum malaria in nonimmune adults and a major contributor to their mortality. In children, renal failure, though not very common, has become a rising issue leading to death. This study aims at determining the incidence of renal complication in malaria cases reported in children of Odisha. 108 cases of malaria who were admitted to Department of Paediatrics, SCB Medical College and Hospital and Sardar Vallab Bhai Patel Post Graduate Institute of Paediatrics, Cuttack, Odisha, India during the period from July 2006 to November 2008 were included in the prospective study. Extensive investigations were carried out to check for renal involvement in these cases. 50.9% of cases showed some form of renal involvement, most of which were recorded in age group of 5–10 years. Overall, males had a higher incidence than females. 62.7% of total cases infected with P. falciparum showed renal involvement though mixed infections with both P. falciparum and P. vivax had 100% renal involvement.