Clinical Study
Effect of Telmisartan on Cerebral and Systemic Haemodynamics in Patients with Recent Ischaemic Stroke: A Randomised Controlled Trial
Table 2
Baseline haemodynamic measures. Mean (standard deviation) number of subjects.
| Characteristic | Telmisartan | Placebo |
| Blood pressure (mmHg) versus 7 | | | Systolic BP | 168.1 (21.3) | 157.7 (21.4) | Mean arterial BP | 117.4 (14.6) | 113.1 (14.2) | Diastolic BP | 91.6 (16.8) | 90.9 (12.4) | Heart rate (bpm) | 69.6 (15.8) | 74.6 (14.6) | Cerebral blood flow, ipsilateral hemisphere (mL/min/100 g) versus 7 | | | Global | 42.2 (13.5) | 47.3 (20.9) | Hemispheric | 42.1 (14.3) | 45.7 (19.7) | Anterior cerebral artery | 42.0 (13.2) | 45.4 (25.7) | Middle cerebral artery | 48.1 (23.3) | 45.5 (20.3) | Posterior cerebral artery | 44.6 (18.9) | 47.8 (24.9) | Cerebral blood flow, contralateral hemisphere (mL/min/100 g) versus 7 | | | Global | | | Hemispheric | 42.6 (12.8) | 50.1 (22.8) | Anterior cerebral artery | 48.2 (16.5) | 49.2 (27.1) | Middle cerebral artery | 49.1 (18.4) | 53.3 (23.8) | Posterior cerebral artery | 42.4 (12.6) | 44.8 (23.9) | Lesion area (pixels) versus 7 | | | Total | 1102 (884) | 1082 (688) | Oligaemia | 240 (146) | 237 (176) | Penumbra | 200 (302) | 162 (190) | Core | 268 (511) | 264 (561) | Transcranial doppler measures, ipsilateral versus 5 | | | Systolic cerebral blood flow velocity (cm/s) | 65.9 (20.1) | 51.2 (16.3) | Pulsatility index | 1.06 (0.20) | 1.08 (0.21) | Cerebral perfusion pressure | 66.8 (14.2) | 58.6 (13.6) | Zero filling pressure | 48.3 (16.3) | 58.1 (3.2) |
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