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ISRN Radiology
Volume 2013 (2013), Article ID 602707, 17 pages
Review Article

Understanding the Role of Hemodynamics in the Initiation, Progression, Rupture, and Treatment Outcome of Cerebral Aneurysm from Medical Image-Based Computational Studies

Grupo de Investigación y Desarrollo en Bioingeniería, Facultad Regional Buenos Aires, Universidad Tecnológica Nacional, CONICET, Medrano 951, CP 1179, Buenos Aires, Argentina

Received 15 May 2013; Accepted 19 June 2013

Academic Editors: H. Akan, J. E. Kim, and V. D. Souftas

Copyright © 2013 Marcelo A. Castro. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


About a decade ago, the first image-based computational hemodynamic studies of cerebral aneurysms were presented. Their potential for clinical applications was the result of a right combination of medical image processing, vascular reconstruction, and grid generation techniques used to reconstruct personalized domains for computational fluid and solid dynamics solvers and data analysis and visualization techniques. A considerable number of studies have captivated the attention of clinicians, neurosurgeons, and neuroradiologists, who realized the ability of those tools to help in understanding the role played by hemodynamics in the natural history and management of intracranial aneurysms. This paper intends to summarize the most relevant results in the field reported during the last years.