Conservation of the Nuclear Receptor Response Element in HIV-1 LTRs: A Possible PPAR Response Element?
Figure 1
The location of the NRRE-1-DE in the HIV-1 5′-LTR. (a) The HIV-1 genome has a 5′-LTR, protein coding sequences (gag, pol, vif, vpr, tat, rev, vpu, env, vif) and a 3′-LTR (adapted from Figure 1 in [32]). The NRRE-1-DE is located within the modulatory region of the 5′-LTR. The nucleotides are numbered below the diagram according to their location upstream of the TAR element, which is denoted as nucleotide +1. Numbering beginning from the 5′-end of the LTR is also indicated above the diagram. (b) The sequence of the NRRE-1-DE, with the D and E heptanucleotide repeats, is indicated above the sequence (adapted from Figures 1(a) and 2(a) in [5]).
