International Scholarly Research Notices / 2013 / Article / Fig 1

Research Article

Genotyping of CYP2D6 Polymorphisms by MALDI-TOF Mass Spectrometry in Sardinian People

Figure 1

An example of 15–plex mass spectrum is shown (Well 5). List of SNPs investigated in this plex is shown in Table 3. The figure shows two examples highlighted in different colours. Unextend primer (UEP) peak is marked by an asterisk and dotted arrow, while the solid arrows indicate the presence of the two different alleles. Dotted vertical lines represent UEPs and extended primers (EPs) expected masses. In blue, an AG heterozygous genotype example is shown. *: −1235A>G UEP; expected mass = 5084 Dalton (Da). G: −1235A>G EP; expected mass = 5332 Da. A: −1235A>G EP; expected mass = 5411 Da. In red, a CC wild type homozygous genotype example is shown. *: 82C>T UEP; expected mass = 5830 Da. T: 82C>T not EP; expected mass = 6101 Da. C: 82C>T EP; expected mass = 6117 Da.
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