International Scholarly Research Notices / 2013 / Article / Tab 9

Research Article

Stability Indicating HPTLC Method for Analysis of Rifaximin in Pharmaceutical Formulations and an Application to Acidic Degradation Kinetic Study

Table 9

Statistical comparison of the results obtained by the proposed HPTLC method in comparison to the reported HPLC method.

ParameterHPTLCHPLC*

Mean % found for analysis of
RCIFAX tablet formulationa
96.6999.59
TORFIX tablet formulationa
test (39)b
98.02
98.48
Formulation analysisa1.15
Intraday precisiona3.87
Interday precisiona
-test (2.776)b
3.61
Formulation analysisa2.38
Intraday precisiona0.32
Interday precisiona0.22

Reported HPLC method using sodium acetate buffer (pH 4.0): acetonitrile (35 : 65 v/v), at 441 nm; aaverage of three determinations; bthe values in the parenthesis represent corresponding tabulated values of and at .

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