CD47: A Cell Surface Glycoprotein Which Regulates Multiple Functions of Hematopoietic Cells in Health and Disease

Figure 3

Association of CD47 with the Rh and band 3 complexes in the erythrocyte membrane. CD47 interacts with the Rh/RhAG complex and also associates with protein 4.2, which links CD47 to the band 3/ankyrin complex and the spectrin cytoskeleton. It is important to note that not all CD47 appears to be associated with this multiprotein complex in erythrocyte membranes.