Research Article

An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst

Table 4

Reusability of P(4-VPH)HSO4 for the synthesis of bis(3-indolyl)phenylmethanea.

RunCycleYieldb (%)

1094
2193
3292
4392
5490
6588

Reaction conditions: indole (2 mmol), benzaldehyde (1 mmol), and P(4-VPH)HSO4 (15 mg), grinding at RT for 12 min.
Isolated yields.