Table of Contents
ISRN Radiology
Volume 2013 (2013), Article ID 627303, 7 pages
http://dx.doi.org/10.5402/2013/627303
Research Article

Alzheimer’s Disease Detection in Brain Magnetic Resonance Images Using Multiscale Fractal Analysis

Department of Computer Science, University of Quebec at Montreal, 201 President-Kennedy, Local PK-4150, Montreal, QC, Canada H2X 3Y7

Received 15 July 2013; Accepted 19 September 2013

Academic Editors: P. A. Narayana and K. Tsuchiya

Copyright © 2013 Salim Lahmiri and Mounir Boukadoum. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We present a new automated system for the detection of brain magnetic resonance images (MRI) affected by Alzheimer’s disease (AD). The MRI is analyzed by means of multiscale analysis (MSA) to obtain its fractals at six different scales. The extracted fractals are used as features to differentiate healthy brain MRI from those of AD by a support vector machine (SVM) classifier. The result of classifying 93 brain MRIs consisting of 51 images of healthy brains and 42 of brains affected by AD, using leave-one-out cross-validation method, yielded classification accuracy, 100% sensitivity, and specificity. These results and a processing time of 5.64 seconds indicate that the proposed approach may be an efficient diagnostic aid for radiologists in the screening for AD.