DLK1 Protein Expression during Mouse Development Provides New Insights into Its Function

Table 1

Overview of DLK1 protein expression during mouse embryonic development.

Organ	ED10	ED13	ED16	ED18
CNS	++	−	−	−
Pituitary	++	++	+++	+
Liver	+++	+++	++	−
Lung	++	++	++	+
Pancreas	+++	++	++	−
Adrenal gland	+	+	++	++
Somites	++
Muscle	NI	++	++	−
Tongue	+++	++	++	−
Vertebrae	NI	++	++	−
Mesonephros/kidney	−	−	−	−
Heart	−	−	−	−
Stomach	−	−	−	−
Intestine	−	−	−	−

NI: not identifiable.
+++: highly positive dark blue staining as shown in Figure 3(A).
++: positive blue staining as shown in Figures 3(D) and 3(E).
+: moderately positive light blue staining as shown in Figure 3(G).
−: no staining.
CNS: central nervous system.