Variable-Temperature Size Exclusion Chromatography for the Study of the Structural Changes in G-Quadruplex

Table 1

Thermodynamic parameters related to the unfolding of the three sequences studied in this work. Experiments have been performed at least three times. Parameters are done in terms of mean value and standard deviation.

Sequence	Δ𝐻^0 (kcal·mol^−1)	Δ𝑆^0 (cal·K^−1·mol^−1)	Δ𝐺^0 (kcal·mol^−1) at 37°C	𝑇𝑚 (°C)	Reference
ckit21	51±3	145±9	5.4±0.6	74±1	This work
ckit21T	46	130	5.8	82	[12]
ckit21T18	44±2	131±3	3.8±0.4	66±2	This work
ckit21T21	46±4	135±12	4.5±0.4	71±1	This work