Exploring Anorectal Manometry as a Method to Study the Effect of Locally Administered Ropivacaine in Patients with Ulcerative Colitis

Table 4

Resting pressure and squeeze pressure recorded before start of treatment (baseline) and after two days and one and four weeks of treatments with 150 mg ropivacaine gel for four weeks in patients with distal UC.

Time (𝑛=7)	Resting pressure		Squeeze pressure		Resting pressure		Squeeze pressure controls
(mmHg)	Median	Min/max	Median	Min/max	Median	Min/max	Median	Min/max
Baseline	113	91/128	198	143/208	63	28/79	92	49/158
Day 2	110	92/127	198	142/206
Week 1*	112	105/133	170	133/215
Week 4	108	96/137	174	131/195

* 𝑛=6.