Gastrointestinal Elimination of Perfluorinated Compounds Using Cholestyramine and Chlorella pyrenoidosa
Table 1
Removal of persistent perfluorinated compounds with cholestyramine (CSM) and Chlorella pyrenoidosa (CP)—female subjects. Objective. To assess whether CSM is consistently effective at removing PFCs from 4 female patients with high PFC levels; posttreatment stool level: after daily CSM or after daily CP. Units—ng/g: blood and ng/g: stool.
Subject
Type of test
PFHxS
PFOS
PFOA
PFNA
#1 female 48
Serum
16.3**
5.67
1.27
0
Pretreatment stool
1.0
<1.0
<1.0
<1.0
Post-CSM stool
3.4
1.0
1.1
<1.0
Post-CP stool
<1.0
<1.0
<1.0
<1.0
#2 female 24
Serum
35.8**
26.5
2.17
0
Pretreatment stool
<1.0
<1.0
<1.0
<1.0
Post-CSM stool
460
2.1
2.1
<1.0
Post-CP stool
<1.0
<1.0
<1.0
<1.0
#3 female 22
Serum
44.1**
27.3
2.33
0.74
Pretreatment stool
<1.0
1.4
<1.0
<1.0
Post-CSM stool
16
5.3
<1.0
<1.0
Post-Chlorella stool
<1.0
1.1
<1.0
<1.0
#4 female 20
Serum
97.5**
44.7
5.04
0.62
Pretreatment stool
1.7
1.5
<1.0
<1.0
Post-CSM stool
26.6
36.9
2
<1.0
Post-CP stool
1.1
<1.0
<1.0
<1.0
Denotes PFC serum value above 95th percentile, NHANES study.