Research Article

Gastrointestinal Elimination of Perfluorinated Compounds Using Cholestyramine and Chlorella pyrenoidosa

Table 1

Removal of persistent perfluorinated compounds with cholestyramine (CSM) and Chlorella  pyrenoidosa (CP)—female subjects. Objective. To assess whether CSM is consistently effective at removing PFCs from 4 female patients with high PFC levels; posttreatment stool level: after daily CSM or after daily CP. Units—ng/g: blood and ng/g: stool.

SubjectType of testPFHxSPFOSPFOAPFNA

#1 female 48Serum16.3**5.671.270
Pretreatment stool1.0<1.0<1.0<1.0
Post-CSM stool3.41.01.1<1.0
Post-CP stool <1.0<1.0<1.0<1.0

#2 female 24Serum35.8**26.52.170
Pretreatment stool<1.0<1.0<1.0<1.0
Post-CSM stool4602.12.1<1.0
Post-CP stool<1.0<1.0<1.0<1.0

#3 female 22Serum44.1**27.32.330.74
Pretreatment stool<1.01.4<1.0<1.0
Post-CSM stool165.3<1.0<1.0
Post-Chlorella stool<1.01.1<1.0<1.0

#4 female 20 Serum97.5**44.75.040.62
Pretreatment stool1.71.5<1.0<1.0
Post-CSM stool26.636.92<1.0
Post-CP stool1.1<1.0<1.0<1.0

Denotes PFC serum value above 95th percentile, NHANES study.