Research Article

Gastrointestinal Elimination of Perfluorinated Compounds Using Cholestyramine and Chlorella pyrenoidosa

Table 2

Removal of persistent perfluorinated compounds with cholestyramine and chlorella—male Subjects. Objective. To assess whether CSM is consistently effective at removing PFCs from 4 male patients with high PFC levels; posttreatment stool level: after daily CSM or after daily CP. Units—ng/g: blood and ng/g: stool.

SubjectType of testPFHxSPFOSPFOAPFNA

#5 male 54Serum34.5**8.581.970
Pretreatment stool<1.0<1.0<1.0<1.0
Post-CSM stool59.44.1<1.0<1.0
Post-CP stool<1.0<1.0<1.0<1.0

#6 male 25Serum30.3**11.33.990.89
Pretreatment stool11.3<1.01.1
Post-CSM Stool13.7<1.01.4<1.0
Post-CP Stool<1.0<1.0<1.0<1.0

#7 male 19Serum92.1**58.85.130.54
Pretreatment stool1.1<1.0<1.0<1.0
Post-CSM Stool30.123.41.2<1.0
Post-CP Stool<1.0<1.0<1.0<1.0

#8 male 17Serum46.5**37.53.990
Pretreatment stool1.8<1.0<1.0<1.0
Post-CSM Stool24.74.51.3<1.0
Post-CP Stool1.2<1.0<1.0<1.0

Denotes PFC serum value above 95th percentile, NHANES study.