Table of Contents
ISRN Pain
Volume 2013, Article ID 671503, 10 pages
http://dx.doi.org/10.1155/2013/671503
Research Article

Neural Mechanisms That Underlie Angina-Induced Referred Pain in the Trigeminal Nerve Territory: A c-Fos Study in Rats

1Department of Physiology, Showa University School of Dentistry, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan
2Department of Physical Therapy, Teikyo Heisei University Faculty of Community Health Care, 4-1 Uruido Minami, Ichihara, Chiba 290-0193, Japan

Received 31 May 2013; Accepted 8 July 2013

Academic Editors: C. M. Cendán, M. I. Díaz-Reval, C. Forster, C.-L. Hsieh, and C. Laurido

Copyright © 2013 Bunsho Hayashi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. D. Foreman, “Mechanisms of cardiac pain,” Annual Review of Physiology, vol. 61, pp. 143–167, 1999. View at Publisher · View at Google Scholar · View at Scopus
  2. T. C. Ruch, “Visceral sensation and referred pain,” in Fulton, Howell’s Textbook of Physiology, pp. 385–401, WB Saunders, Philadelphia, Pa, USA, 15th edition, 1946. View at Google Scholar
  3. D. E. Myers, “Vagus nerve pain referred to the craniofacial region. A case report and literature review with implications for referred cardiac pain,” The British Dental Journal, vol. 204, no. 4, pp. 187–189, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. M. J. Chandler, J. Zhang, and R. D. Foreman, “Vagal, sympathetic and somatic sensory inputs to upper cervical (C1-C3) spinothalamic tract neurons in monkeys,” Journal of Neurophysiology, vol. 76, no. 4, pp. 2555–2567, 1996. View at Google Scholar · View at Scopus
  5. M. J. Chandler, J. Zhang, and R. D. Foreman, “Pericardial injections of inflammatory chemicals excite upper cervical (C1-C3) spinothalamic tract (STT) cells in monkeys,” Society for Neuroscience, vol. 21, article 2604, 1995. View at Google Scholar
  6. R. D. Foreman and C. Qin, “Neuromodulation of cardiac pain and cerebral vasculature: neural mechanisms,” Cleveland Clinic Journal of Medicine, vol. 76, pp. S75–S79, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. C. Qin, M. J. Chandler, K. E. Miller, and R. D. Foreman, “Responses and afferent pathways of superficial and deeper C1-C2 spinal cells to intrapericardial algogenic chemicals in rats,” Journal of Neurophysiology, vol. 85, no. 4, pp. 1522–1532, 2001. View at Google Scholar · View at Scopus
  8. D. L. McNeill, M. J. Chandler, Q. G. Fu, and R. D. Foreman, “Projection of nodose ganglion cells to the upper cervical spinal cord in the rat,” Brain Research Bulletin, vol. 27, no. 2, pp. 151–155, 1991. View at Publisher · View at Google Scholar · View at Scopus
  9. B. J. Sessle, “Peripheral and central mechanisms of orofacial inflammatory pain,” International Review of Neurobiology, vol. 97, pp. 179–206, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. B. Greenwood-Van Meerveld, M. Gibson, W. Gunter, J. Shepard, R. Foreman, and D. Myers, “Stereotaxic delivery of corticosterone to the amygdala modulates colonic sensitivity in rats,” Brain Research, vol. 893, no. 1-2, pp. 135–142, 2001. View at Publisher · View at Google Scholar · View at Scopus
  11. W. D. Gunter, J. D. Shepard, R. D. Foreman, D. A. Myers, and B. Greenwood-Van Meerveld, “Evidence for visceral hypersensitivity in high-anxiety rats,” Physiology and Behavior, vol. 69, no. 3, pp. 379–382, 2000. View at Publisher · View at Google Scholar · View at Scopus
  12. C. Qin, B. Greenwood-Van Meerveld, D. A. Myers, and R. D. Foreman, “Corticosterone acts directly at the amygdala to alter spinal neuronal activity in response to colorectal distension,” Journal of Neurophysiology, vol. 89, no. 3, pp. 1343–1352, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. J. C. White and W. H. Seet, Eds., Pain and the Neurosurgeon, Charles C. Thomas, Springfield, Ill, USA, 1969.
  14. F. Hua, T. Harrison, C. Qin et al., “c-Fos expression in rat brain stem and spinal cord in response to activation of cardiac ischemia-sensitive afferent neurons and electrostimulatory modulation,” The American Journal of Physiology—Heart and Circulatory Physiology, vol. 287, no. 6, pp. H2728–H2738, 2004. View at Publisher · View at Google Scholar · View at Scopus
  15. I. Lindgren and H. Olivecrona, “Surgical treatment of angina pectoris,” Journal of Neurosurgery, vol. 4, no. 1, pp. 19–39, 1947. View at Publisher · View at Google Scholar
  16. J. C. White and E. F. Bland, “The surgical relief of severe angina pectoris: methods employed and end,” Medicine, vol. 27, no. 1, pp. 1–42, 1948. View at Google Scholar · View at Scopus
  17. M. Zimmermann, “Ethical guidelines for investigations of experimental pain in conscious animals,” Pain, vol. 16, no. 2, pp. 109–110, 1983. View at Publisher · View at Google Scholar · View at Scopus
  18. H. O. Handwerker and P. W. Reeh :, “Pain and inflammation,” in Proceedings of the 5th World Congress on Pain, M. R. Bond, J. E. Charlton, and C. J. Woolf, Eds., pp. 59–70, Elsevier, Amsterdam, The Netherlands, 1991. View at Google Scholar
  19. I. Euchner-Wamser, S. T. Meller, and G. F. Gebhart, “A model of cardiac nociception in chronically instrumented rats: behavioral and electrophysiological effects of pericardial administration of algogenic substances,” Pain, vol. 58, no. 1, pp. 117–128, 1994. View at Publisher · View at Google Scholar · View at Scopus
  20. S. T. Meller and G. F. Gebhart, “A critical review of the afferent pathways and the potential chemical mediators involved in cardiac pain,” Neuroscience, vol. 48, no. 3, pp. 501–524, 1992. View at Publisher · View at Google Scholar · View at Scopus
  21. G. Paxinos and C. Watson, Eds., The Rat Brain in Stereotaxic Coodinates, Academic Press, New York, NY, USA, 1998.
  22. M. E. Edelsbrunner, M. Nakano, and P. Holzer, “Afferent signalling from the acid-challenged rat stomach is inhibited and gastric acid elimination is enhanced by lafutidine,” BMC Gastroenterology, vol. 9, article 40, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. T. Haino, S. Hironaka, T. Ooka et al., “Orosensory deprivation alters taste-elicited c-Fos expression in the parabrachial nucleus of neonatal rats,” Neuroscience Research, vol. 67, no. 3, pp. 228–235, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. K. Okamoto, R. Thompson, A. Tashiro, Z. Chang, and D. A. Bereiter, “Bright light produces Fos-positive neurons in caudal trigeminal brainstem,” Neuroscience, vol. 160, no. 4, pp. 858–864, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. K. Tokita, T. Shimura, S. Nakamura, T. Inoue, and T. Yamamoto, “Involvement of forebrain in parabrachial neuronal activation induced by aversively conditioned taste stimuli in the rat,” Brain Research, vol. 1141, no. 1, pp. 188–196, 2007. View at Publisher · View at Google Scholar · View at Scopus
  26. T. Yamamoto and K. Sawa, “c-Fos-like immunoreactivity in the brainstem following gastric loads of various chemical solutions in rats,” Brain Research, vol. 866, no. 1-2, pp. 135–143, 2000. View at Publisher · View at Google Scholar · View at Scopus
  27. T. Yamamoto and K. Sawa, “Comparison of c-Fos-like immunoreactivity in the brainstem following intraoral and intragastric infusions of chemical solutions in rats,” Brain Research, vol. 866, no. 1-2, pp. 144–151, 2000. View at Publisher · View at Google Scholar · View at Scopus
  28. T. Yamamoto, M. Takemura, T. Inui et al., “Functional organization of the rodent parabrachial nucleus,” Annals of the New York Academy of Sciences, vol. 1170, pp. 378–382, 2009. View at Publisher · View at Google Scholar · View at Scopus
  29. B. J. Sessle, “Neural mechanisms and pathways in craniofacial pain,” Canadian Journal of Neurological Sciences, vol. 26, no. 3, pp. S7–S11, 1999. View at Google Scholar · View at Scopus
  30. R. Nieuwenhuys, J. Voogd, and C. H. R. van Huijzen, Eds., The Human Central Nervous System. A Synopsis and Atlas, Springer, Berlin, Germany, 1978.
  31. H. Burton, A. D. Craig Jr., D. A. Poulos, and J. T. Molt, “Efferent projections from temperature sensitive recording loci within the marginal zone of the nucleus caudalis of the spinal trigeminal complex in the cat,” Journal of Comparative Neurology, vol. 183, no. 4, pp. 753–777, 1979. View at Google Scholar · View at Scopus
  32. H. Burton and A. D. Loewy, “Descending projections from the marginal cell layer and other regions of the monkey spinal cord,” Brain Research, vol. 116, no. 3, pp. 485–491, 1976. View at Publisher · View at Google Scholar · View at Scopus
  33. C. E. Catsman-Berrevoets and H. G. J. M. Kuypers, “Cells of origin of cortical projections to dorsal column nuclei, spinal cord and bulbar medial reticular formation in the rhesus monkey,” Neuroscience Letters, vol. 3, no. 5-6, pp. 245–252, 1976. View at Google Scholar · View at Scopus
  34. H. G. J. M. Kuypers and V. A. Maisky, “Retrograde axonal transport of horseradish peroxidase from spinal cord to brain stem cell groups in the cat,” Neuroscience Letters, vol. 1, no. 1, pp. 9–14, 1975. View at Google Scholar · View at Scopus
  35. D. A. Ruggiero, C. A. Ross, and D. J. Reis, “Projections from the spinal trigeminal nucleus to the entire length of the spinal cord in the rat,” Brain Research, vol. 225, no. 2, pp. 225–233, 1981. View at Publisher · View at Google Scholar · View at Scopus