Table 2: Comparative analysis between patients with and without thyroid nodules in Graves’ disease and Hashimoto’s thyroiditis.

Graves' disease ( = 198)Hashimoto’s thyroiditis ( = 77)
With nodulesWithout nodules With nodulesWithout nodules

Gender—male/female (%)4/51 (2.02/25.76)14/129 (7.07/65.15)0.5812/37 (2.6/48.05)3/35 (3.9/45.45)0.675
Age—yrs (range)53 (27–84)43 (13–82.8)<0.00155 (15–84)49.5 (17–79)0.421
Age at diagnosis—yrs (range)46 (17–81)36 (9–77)<0.00147 (5–70)43.5 (14–77)0.194
Disease duration—yrs (range)6 (0.6–20)5.0 (0.5–27)0.0747 (0.2–16)7 (0.1–21)0.953
Total thyroid volume—cc (range)29.8 (4.1–242)23.1 (1.6–201.3)0.01918.5 (1–111.9)9.8 (2.1–69.2)0.005
Time of followup—yrs (range)6 (0.3–20)5 (0.1–20)0.0777 (0.2–16)7 (0.1–21)0.779
Smoking (%)a18 (13.53)49 (36.84)0.8859 (26.47)5 (14.71)1.0
Time of treatment—yrs (range)4 (0.3–17)3 (0.1–20)0.4336 (1–16)7 (1–15)0.945
Ophthalmopathy (%)b22 (16.06)70 (51.09)0.077NANANA
Active disease (%)50 (25.25)126 (63.64)0.575NANANA
Radioiodine treatment (%)17 (8.59)49 (24.75)0.654NANANA
99mTc uptake—% (range)7 (0.2–82)10 (0.3–77)0.138NANANA

a = 133 for GD and = 34 for HT.
b = 137 for GD.
NA: not available.