Research Article

Hemorrhagic Transformation (HT) and Symptomatic Intracerebral Hemorrhage (sICH) Risk Prediction Models for Postthrombolytic Hemorrhage in the Stroke Belt

Table 3

Odds of sICH according to selected scoring methodologies in our cohort of Stroke Belt patients.

Odds of sICH
OR95% CI value

Entire population
  Cucchiara score
   4 groups (1, 2, 3, 4)2.021.08–3.810.0287
   2 groups (>=3)3.420.90–12.90.0706
  SITS-sICH
   4 groups (0–2, 3–5, 6–8, 9–12)1.510.63–3.630.3593
   2 groups (>=6)1.260.33–4.850.7364
  SPAN-100n/an/an/a
Black patients
  Cucchiara score
   4 groups (1, 2, 3, 4)2.911.10–7.720.0318
   2 groups (>=3)6.031.07–34.10.0422
  SITS-sICH
   4 groups (0–2, 3–5, 6–8, 9–12)1.640.54–4.970.3792
   2 groups (>=6)1.240.24–6.380.8009
  SPAN-100n/an/an/a
White patients
  Cucchiara score
   4 groups (1, 2, 3, 4)1.020.34–3.020.9730
   2 groups (>=3)n/an/an/a
  SITS-sICH
   4 groups (0–2, 3–5, 6–8, 9–12)1.630.39–6.860.5049
   2 groups (>=6)1.780.14–21.920.6535
  SPAN-100n/an/an/a

SPAN-100 model was unable to converge in the present population.
sICH denotes symptomatic intracranial hemorrhage; OR: odds ratio; CI: confidence interval; SITS: safe implementation of treatments in stroke; SPAN-100: stroke prognostication using age and National Institutes of Health Stroke Scale score.