Effect of Two Different Doses of Gabapentin on the Intraocular Pressure and Hemodynamic Stress Responses to Laryngoscopy and Tracheal Intubation

Table 4

IOP (mean) at various intervals in the different groups.

	Control (no. 20)	Gaptin 800 (no. 20)	Gaptin 1200 (no. 20)	𝐹	𝑃
Baseline	15.05 ± 2.704	16.27 ± 2.67	15.7 ± 2.61	1.1	0.33
After induction	12.35 ± 2.39*	12.95 ± 2.33**	11.77 ± 2.18**	1.31	0.27
After intubation	18.950 ± 2.98^#**	16.37 ± 2.51^@	13.6 ± 2.28**	31.05	0.000
5 min	17 ± 2.59^#*	15.15 ± 2.32^@**	12.65 ± 2.05**	17.55	0.000
10 min	15.95 ± 2.63^#	14.15 ± 2.65^@**	12.02 ± 2.11**	12.62	0.000
𝑃	0.000	0.000	0.000

Data were expressed as mean ± SD.
^#Means that control group was significantly different from both groups (𝑃<0.05).
^@Means that gabapentin 800 group was significantly different from gabapentin 1200 group (𝑃<0.05).
*Means significant difference from baseline value (𝑃<0.05).
**Means highly significant difference from baseline value (𝑃<0.001).