Table of Contents
ISRN Neurology
Volume 2013 (2013), Article ID 710681, 4 pages
http://dx.doi.org/10.1155/2013/710681
Research Article

Age Predicts Functional Outcome in Acute Stroke Patients with rt-PA Treatment

1Department of Medicine, Faculty of Medicine, Khon Kaen University, 123 Mitraparp Road, Khon Kaen 40002, Thailand
2Improvement of Physical Performance and Quality of Life Research Group, Khon Kaen University, Khon Kaen 40002, Thailand
3Researches and Diagnostic Center for Emerging Infectious Diseases, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
4North-Eastern Stroke Research Group, Khon Kaen University, Khon Kaen 40002, Thailand
5Stroke Unit, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand

Received 29 July 2013; Accepted 18 August 2013

Academic Editors: A. Arboix, G. Boysen, and M. G. Grasso

Copyright © 2013 Jarin Chindaprasirt et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The standard treatment for acute ischemic stroke is thrombolytic therapy. There is limited data on prognostic factors of acute stroke with thrombolytic therapy particularly in Asian population. Acute ischemic stroke patients who were treated with thrombolytic therapy at Srinagarind Hospital between May 2008 and July 2010 were included. Factors associated with Barthel index more than 80 were studied by multiple logistic regression analysis. There were 75 patients included in the study. The mean NIHSS scores before treatment and at 3 months were 9.16 ± 4.82 and 3.83 ± 4.00, respectively, and median Barthel index at 3 months was 86. Only significant predictor for having Barthel index more than 80 points at 3 months was age (adjusted odds ratio 0.929, 95% confidence interval 0.874, 0.988). Four patients developed intracranial hemorrhage after the treatment (5%), and two died (2.6%). In conclusion, age predicts Barthel index in acute stroke patients with rt-PA treatment.