Clinical Study

Clinicopathological Features of Growth Hormone-Producing Pituitary Adenomas in 242 Acromegaly Patients: Classification according to Hormone Production and Cytokeratin Distribution

Table 1

Clinical data of all subjects.

Age48.0 ± 12.9
Sex (M/F)107/135
GH (basal) (ng/mL)17.3 ± 48.3
IGF-1 (U/mL)602 ± 259
PRL (ng/mL)27.5 ± 63.1
TSH (μIU/mL)0.8 ± 0.7
Maximum tumor diameter (mm)16.8 ± 8.6
Micro (−10 mm)/Macro (>10 mm)62/180
Tumor volume (cm3)2.2 ± 4.7
Knosp (3,4)24%
Sphenoid sinus invasion15%

M: male; F: female; GH: growth hormone; IGF-1: insulin-like growth factor-1; PRL: prolactin; TSH: thyroid stimulating hormone.