Tumor Inhibition by DepoVax-Based Cancer Vaccine Is Accompanied by Reduced Regulatory/Suppressor Cell Proliferation and Tumor Infiltration
Figure 3
Percentages of MDSCs in the spleen (a) and blood (b) of C3 tumor-challenged mice at week five after challenge. Groups of tumor implanted mice were injected 6 days later with PBS alone, vaccinated using DPX-E7 vaccine, or injected as CE vaccine emulsion. Percentages of CD11b+Gr1+ MDSCs in spleen and blood were determined using flow-cytometry. Data represents mean ± SDM from 5 mice per group and from one of three experiments with similar findings.
