Retina degeneration (especially MPSI, MPSII, and MPSIII) [32, 36]
Sensor neural deafness (common to all MPS types) [19, 32]
Chronic catarrhal otitis transtympanic drainage (common to all MPS types) [19, 32] AIEOP-SIMMESN/recommendations MPS I/25.10.2010
Obstructive sleep apnea (OSA) (common to all MPS types) [32, 38]
OSA adenotonsillectomy, laser excision of tracheal lesions, and tracheotomy (common to all MPS types) [6, 19, 32] AIEOP-SIMMESN/recommendations MPS I/25.10.2010