Table of Contents
ISRN Nanomaterials
Volume 2013, Article ID 801242, 5 pages
Review Article

Should Experimental Chemists Be Doing More to Help Evaluate the Toxicological Potential of Nanoparticles?

Molecular Structure Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69009 Heidelberg, Germany

Received 30 June 2013; Accepted 27 July 2013

Academic Editors: J. Bai and Y. Zhang

Copyright © 2013 Karel D. Klika. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


More general testing of nanoparticles (NP) for properties that are amenable towards biological activity, and thus potentially conducive to nanotoxicity, should be conducted on a broader scale by experimental chemists to help assess the pernicious threat that NP may present to human health or to the environment. For example, evaluation by measuring NP-biomolecule bioaffinity using techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR) is advocated, thereby echoing a similar call to computational and theoretical chemists to expand their studies and make at least part of their work, where feasible, relevant to nanotoxicity.