Clinical Presentation, Pathogenesis, Diagnosis, and Treatment of Epidermolysis Bullosa Acquisita

Table 1

Epidemiology and Ig reactivity in EBA.

Gender distribution	61% female; 39% male
Age (median, 75 percentile)	47, 30–66 years*
Clinical phenotypes	Inflammatory phenotypes: 66%; Classical (mechanobullous) phenotype: 33%
Ig reactivity (DIF positive)	IgG: 39%; IgA: 19%; IgG and IgA: 35%; Not detected: 7%

∗Black EBA patients with African descent have a significantly younger age when diagnosed compared to cohorts in Korea or the Netherlands. Abbreviations used: DIF: direct immunofluorescence microscopy. Data is based on 83 EBA patients [6–8].