International Scholarly Research Notices / 2013 / Article / Tab 4

Research Article

Genotoxicological Evaluation of NUTRALYS Pea Protein Isolate

Table 4

Percentage Mitotic Index.

% Mitotic index (MI)
Concentration* (µg/mL)3h with S9 (10%)3h without S9Continuous without S9
%MI% MI inhibition**%MI% MI inhibition**%MI% MI inhibition**

Solvent control
(sterile millipore water 50  L/5 mL culture)
3.0 —2.35 —3.1 —
125@2.6511.662.4−2.132.954.84
250@2.93.332.95−25.533.55−14.52
500@2.86.672.85−21.282.858.06
Positive control#2.613.331.727.661.6546.77

Mean value of duplicate cultures.
20 µg/mL cyclophosphamide (with S9); 0.8  g/mL mitomycin C (without S9).
Moderate sedimentation of test substance on slides.
% MI inhibition = × 100.

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