Genotoxicological Evaluation of NUTRALYS Pea Protein Isolate
Table 4
Percentage Mitotic Index.
% Mitotic index (MI)
Concentration* (µg/mL)
3h with S9 (10%)
3h without S9
Continuous without S9
%MI
% MI inhibition**
%MI
% MI inhibition**
%MI
% MI inhibition**
Solvent control (sterile millipore water 50 L/5 mL culture)
3.0
—
2.35
—
3.1
—
125@
2.65
11.66
2.4
−2.13
2.95
4.84
250@
2.9
3.33
2.95
−25.53
3.55
−14.52
500@
2.8
6.67
2.85
−21.28
2.85
8.06
Positive control#
2.6
13.33
1.7
27.66
1.65
46.77
Mean value of duplicate cultures. 20 µg/mL cyclophosphamide (with S9); 0.8 g/mL mitomycin C (without S9). Moderate sedimentation of test substance on slides. % MI inhibition = × 100.
