Research Article

Carbofuran Induced Oxidative Stress in Rat Heart: Ameliorative Effect of Vitamin C

Table 4

Effect of carbofuran and vitamin C on level of MDA, total thiol, and GSH in heart tissues.

Level of MDAaLevel of total thiolbLevel of GSHb

Control
5% CF (+30.87%) (+37.9%) (+63%)
10% CF (+65%) (+156%) (+263%)
Vit C ns ns ns
Vit C + 5% CF ns ns ns
Vit C + 10% CF ns ns ns

(nmoles of MDA mg−1 protein), b( g mg−1 protein); the (+) sign shows increase in the MDA and GSH contents. The values are mean ± SD of five independent experiments. The procedure for estimation of MDA and GSH was the same as mentioned in Section 2. ns: nonsignificant. ** and *** indicate the values significance at 0.01 and 0.001, respectively. ns: nonsignificant at as compared to control.