Carbofuran Induced Oxidative Stress in Rat Heart: Ameliorative Effect of Vitamin C

Table 6

Effect of carbofuran and vitamin C on level of total cholesterol and HDL in serum.

Level of lipids	Control	5% CF	10% CF	Vit. C	Vit. C + 5% CF	Vit. C + 10% CF
Total cholesterol^a	189.7±12.36	278.7±13.28^∗∗∗ (+47%)	335.0±28.52^∗∗∗ (+77%)	169.9±15.09^ns	211.7±9.409^ns	227.7±13.41^∗
HDL^a	39.69±5.41	25.54±2.17^∗∗∗ (−35%)	14.98±3.04^∗∗∗ (−64%)	41.12±2.67^ns	33.54±2.78^ns	32.14±2.10^∗

amg dL⁻¹; the (−) and (+) signs show decrease and increase, respectively, in the levels of cholesterol and HDL. The values are mean ± SD of five independent experiments. The procedures for estimation of the activities of the enzymes were as mentioned in Section 2. * and *** indicate the 𝑃 values significance at <0.05 and <0.001, respectively. ns: nonsignificant at 𝑃>0.05 as compared to control.