A Practical Update of Surgical Management of Merkel Cell Carcinoma of the Skin

Table 1

Pathology diagnosis of MCC.

(1) Perform fine needle aspiration cytology or biopsy of different lesions in the same patient.
(2) Section skin specimen thoroughly to avoid missing the aggressive MCC component since it can coexist with other more common skin cancers.
(3) Immunostaining for cytokeratin-20 can detect micrometastasis in sentinel nodes.