Clinical Study

Stronger Correlation between Interleukin 18 and Soluble Fas in Lupus Nephritis Compared with Mild Lupus

Table 1

Important demographic and laboratory data of the patients.

VariablesTotal patients ( )
mean (±SD) or IQR*
Patients without proteinuria ( )
mean (±SD) or IQR
Patients with proteinuria ( )
mean (±SD) or IQR
value (patients with and without proteinuria)

Age (years)
range
30.14 (±9.5)
15–62
28.98 (±6.8)
20–43
29.47 (±8.9)
15–62
0.6**
C3 (mg/dL)
range
41 (30.75–97)
5–163
41 (33–100)
5–163
62.44 (±41.4)
5–150
0.5**
C4 (mg/dL)
range
14 (27–10)
4–53
15 (10–32)
5–35
18.41 (±12.5)
4–49
0.5**
Anti dsDNA
range
2 (1–7)
1–30
4.43 (±5.4)
1–30
1.5 (1–8)
1–15
0.6***
Cr (mg/dL)0.77 (±26)0.78 (±0.26)0.77 (±0.26)0.82**
ESR (mm/h)
range
25 (18–54)
2–150
25 (17–47)
4–119
48.81 (±39.4)
2–150
0.1***
IL-18 (pg/mL)
range
479 (287–775)
20–1245
399.23 (±287.5)
20–1125
615.57 (±342.6)
25–1245
0.02**
sFas (pg/mL)
range
210 (148–195)
1–2260
168 (134–292)
61–810
409.38 (±416.3)
1–2260
0.03**
Number of Lymphopenic patients (%)27 (34.6)17 (36.9)10 (31.25)0.60****
Number of thrombocytopenic patients (%)9 (11.53)5 (10.86)4 (12.5)1****
Number of patients with hemolytic anemia (%)3 (3.8)2 (4.34)1 (3.1)1****

Normally distributed are presented by mean (± SD), not normally distributed data are presented by interquartile (IQR) range.
** Student's t-test.
***Mann-Whitney test.
****Chi-square test.