Spectrophotometric Determination of Bromhexine HCl in Pure and Pharmaceutical Forms

Table 2

Application of proposed methods for the determination of BRH in pure form.

BRH	BTB (A)	BPB (B)	BCG (C)	I2 (D)	KMnO4 (E)
Taken (µg mL^−1)	3.00	3.00	3.00	5.00	20.00
	6.00	6.00	6.00	10.00	25.00
	9.00	9.00	9.00	15.00	30.00
	12.00	12.00	12.00	20.00	35.00
	15.00	15.00	15.00	25.00	40.00
Found (µg mL^−1)	3.01	3.04	3.10	4.99	20.02
	6.05	6.03	6.09	10.05	24.95
	8.99	9.08	9.10	15.02	30.05
	11.98	12.06	12.08	19.95	35.06
	15.10	14.96	14.98	24.96	39.96
Recovery (%)	99.67	98.68	96.77	100.20	99.90
	99.17	99.50	98.52	99.50	100.20
	100.11	99.12	98.90	99.87	99.83
	100.17	99.50	99.34	100.25	99.83
	99.34	100.27	100.13	100.16	100.10
Mean	99.69	99.42	98.73	100.00	99.97
SD	1.50	1.80	1.25	1.60	1.25
Reference method [14]	99.77±0.48	99.77±0.48	99.77±0.48	99.77±0.48	99.77±0.48
𝑡-test (1.10)*	0.11	0.42	1.73	0.31	0.33
𝐹-test (2.61)*	2.25	3.24	1.56	2.56	1.56

Each result is the average of five separate determinations. ∗Values in paranthesis are thetabulated 𝑡 and 𝐹 values, at 𝑃=0.05 [27].