A Dual 5α-Reductase Inhibitor Dutasteride Caused Reductions in Vascular Density and Area in Benign Prostatic Hyperplasia

Table 2

Histological data for the resected BPH tissue.

	Control group	Dutasteride group	𝑃 value
Artery/arteriole density (counts/mm^2)	0.30±0.25	0.13±0.18	0.0328
Vein/venule density (counts/mm^2)	0.92±0.57	0.40±0.28	0.0025
CD31-positive vessel density (counts/mm^2)	3.65±1.46	4.05±1.66	0.5914
Glandular density (counts/mm^2)	4.21±1.96	4.54±3.12	0.9611
Artery/arteriole area relative to the whole area (%)	0.37±0.33	0.18±0.23	0.0563
Vein/venule area relative to the whole area (%)	0.58±0.37	0.29±0.41	0.0084
Glandular area relative to the whole area (%)	7.94±4.17	7.82±6.19	0.6256
CD31-positive vessel area relative to the whole area (%)	1.85±0.74	1.99±1.08	0.8836

Values are expressed as the mean ± SD. 𝑃 values are from the Mann-Whitney 𝑈 test.