Review Article

Neurochemical and Behavioral Features in Genetic Absence Epilepsy and in Acutely Induced Absence Seizures

Figure 1

The schematic representation of two types of epileptic discharges. (a) The gradual increase in potential reaches the threshold level followed by the generation of epileptic discharges. This is typical for the EEG hallmarks accompanying convulsive seizures. (b) The spike-wave discharge. It consists of an inhibitory phase and an action potential. The inhibitory phase (1) appears as a slow wave on the EEG, excitation (a series of action potentials) of the cells appears as a spike (2). A rebound peak appears at the end of this phase and the cycle repeats itself many times. The discharge possesses the same profile as spike-wave discharges (with permission from Springer; [30]).
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(a)
875834.fig.001b
(b)