Maternal Age at First Delivery and Risk of Cardiovascular Disease Later in Life
Table 3
Association between categorized age at first delivery and cardiovascular diseases.
Age at first delivery (years)
≤25 versus 26–30
≤25 versus 31–35
≤25 versus >35
Age-adjusted
Adjusted*
Age-adjusted
Adjusted*
Age-adjusted
Adjusted*
OR
95% CI
OR
95% CI
OR
95% CI
OR
95% CI
OR
95% CI
OR
95% CI
Hypertension
No
Yes
1.28
1.06
1.55
1.12
0.91
1.37
1.50
1.12
2.00
1.38
0.99
1.91
2.73
1.51
4.93
2.15
1.10
4.22
Arrhythmia
No
Yes
1.18
0.93
1.49
1.16
0.88
1.52
1.69
1.10
2.58
1.82
1.13
2.92
1.82
0.96
3.46
1.85
0.84
4.08
Angina pectoris
No
Yes
1.70
1.18
2.47
1.95
1.20
3.17
1.98
1.07
3.67
2.24
0.98
5.09
1.60
0.63
4.09
1.29
0.35
4.74
Myocardial infarction
No
Yes
1.52
0.90
2.57
1.17
0.59
2.34
2.73
0.99
7.49
4.82
1.39
16.75
NC
NC
Heart failure
No
Yes
1.28
0.84
1.95
1.24
0.70
2.19
1.69
0.92
3.10
2.08
0.94
4.60
1.21
0.49
3.02
1.32
0.35
4.92
Stroke
No
Yes
1.09
0.67
1.77
0.84
0.42
1.67
2.05
0.81
5.18
2.35
0.62
8.86
1.28
0.41
4.05
1.07
0.20
5.78
Adjusted for age, total number of pregnancy, education, smoking, BMI, waist/hip ratio, physical activity, systolic and diastolic blood pressure, fasting blood glucose, and total and low-density lipoprotein cholesterol; bold OR: statistically significant; NC: Not calculable.
