Table of Contents
ISRN Stroke
Volume 2013, Article ID 898163, 7 pages
http://dx.doi.org/10.1155/2013/898163
Clinical Study

The Impact of Left Ventricular Hypertrophy and Diastolic Dysfunction on Outcome in Intracerebral Hemorrhage Patients

1Health Services and Outcomes Research Center for Outcome and Effectiveness Research and Education (COERE), University of Alabama at Birmingham, Birmingham, AL 35294-4410, USA
2Center of Excellence in Comparative Effectiveness Research for Eliminating Disparities (CERED) Minority Health & Health Disparities Research Center (MHRC), University of Alabama at Birmingham, Birmingham, AL 35294-4410, USA
3School of Public Health, Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294-0022, USA
4Department of Medicine, Cardiology Section, Tulane University School of Medicine, New Orleans, LA 70112, USA
5Division of Neurosciences Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
6Stroke Program, Department of Neurology, Tulane University School of Medicine, New Orleans, LA 70112, USA
7Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA
8Stroke Program at Tulane University Hospital, Department of Neurology, Suite 1000, 1440 Canal Street, TB-52, New Orleans, LA 70112-2715, USA

Received 3 June 2013; Accepted 18 July 2013

Academic Editors: A. Ducruet, H. C. Emsley, and A. Slivka

Copyright © 2013 Karen C. Albright et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. The objective of this study was to determine the prevalence of LVH and DD in patients presenting with supratentorial deep ICH and to determine if the presence of LVH or DD was an independent predictor of initial ICH volume, hematoma expansion, or poor outcome. Methods. A cross-sectional study was performed on ICH patients who presented from 7/2008 to 12/2010. Cases were excluded if ICH was traumatic, lobar, infratentorial, secondary to elevated international normalized ratio, suspicious for underlying structural malformation, or where surgical evacuation was performed. Logistic and linear regressions were used to assess the ability of LVH to predict ICH imaging characteristics and patient outcomes. Results. After adjusting for use of hemostatic agents, LVH was not a significant independent predictor of initial ICH volume or 33% volume expansion . After adjusting for age, infectious complications, and use of hemostatic agents, LVH was not a significant independent predictor of poor functional outcome . Similar results were seen for DD. Conclusion. In our sample, patients with deep ICH and LVH were more likely to develop IVH, but LVH was not a significant independent predictor of initial ICH volume, hematoma expansion, or poor short-term outcome.