Review Article

Human Immunodeficiency Virus and Pulmonary Arterial Hypertension

Table 1

Classification of PH.

GroupEtiologies

Group 1.Idiopathic, heritable, connective tissue disease, Human immunodeficiency virus infection, portopulmonary hypertension, congenital heart disease, drug/toxin induced, chronic hemolytic anemia, schistosomiasis, persistent PH of the newborn, pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis.

Group 2. PH owing to left heart diseaseSystolic and diastolic dysfunction, mitral and aortic valve diseases.

Group 3. Pulmonary hypertension owing to lung diseases and/or hypoxiaChronic obstructive pulmonary disease, interstitial lung disease, sleep disordered breathing, and so forth.

Group 4. Chronic thromboembolic pulmonary hypertensionUnresolved fibrin thromboembolization to the pulmonary arteries.

Group 5. Pulmonary hypertension with unclear multifactorial mechanismsMyeloproliferative disorders, splenectomy, pulmonary vasculitis, neurofibromatosis, thyroid disorders, and so forth.