Marked Effects of Tachykinin in Myositis Both in the Experimental Side and Contralaterally: Studies on NK-1 Receptor Expressions in an Animal Model
Figure 10
Parts of sections from a soleus muscle specimen, exercised side, 6-week group. In (a)–(c) a normally appearing muscle area is shown, in (d)–(f) a part of a myositis area. The muscle fibers in (a)–(c) are in principle transversely cut, whereas those in (d)–(f) are longitudinally cut. Double staining for desmin and NK-1R. Desmin staining is shown in (a, d), desmin staining coupled to DAPI in (b, e), and NK-1R staining in (c, f). In (a, b), the normal striated desmin immunoreaction pattern is seen. There are no NK-1R immunoreactions in (c). In (e), it is seen that there is a massive infiltration of cells in a part of the muscle fiber (#), and to a certain extent an infiltration in another part (asterisk). The desmin immunoreaction is weak in the middle of the latter part and non-existent in the former. There are NK-1R immunoreactions in infiltrating cells (arrows, (f)). Bar = 25 μm.
