Marked Effects of Tachykinin in Myositis Both in the Experimental Side and Contralaterally: Studies on NK-1 Receptor Expressions in an Animal Model
Figure 11
Section from a soleus muscle specimen, nonexercised side, 6-week group. Double staining for desmin coupled to DAPI (a) and NK-1R (b) is shown. The area is shown in higher magnification in (b) than in (a). There is a very marked desmin immunoreaction in the muscle fiber in the middle (asterisk), and the normal desmin striations cannot be seen in the fiber. These striations can be seen in adjacent muscle fibers. There are point-like NK-1R immunoreactions in this muscle fiber (arrows, (b)) but no NK-1R in adjacent fibers. M1, M2 = muscle fibers. There are internal nuclei in the muscle fiber in the markedly desmin immunoreactive muscle fiber (arrows, (a)). Bar = 25 μm.
