Chromosome Aberrations in Cells Infected with Bovine Papillomavirus: Comparing Cutaneous Papilloma, Esophagus Papilloma, and Urinary Bladder Lesion Cells

Table 2

Frequencies of different aberrations detected in blood and primary culture cells of animals affected by cutaneous papillomas, esophagus papilloma, and enzootic hematuria.

Blood
Group	CA	AT	AF	CB	CrB
C	0.88±1.24	2.48±1.46	2.33±0.81	1.75±2.48	1.60±0.22
1	4.27±2.20^¤	3.86±0.96	7.20±5.27	2.31±2.00	𝟖.𝟔𝟕±𝟑.𝟎𝟑^∗
2	𝟔.𝟎𝟕±𝟏.𝟐𝟖^∗	6.34±5.67	𝟏𝟒.𝟕𝟒±𝟏.𝟏𝟏^∗	1.16±1.64	4.35±3.71
3	1.65±0.39	4.25±2.14	6.86±3.89	0.68±0.97	𝟔.𝟑𝟏±𝟎.𝟕𝟔^∗∗
	Ad/Del	EcrS	Aneu	Polip	Gaps
C	2.33±0.81	0.72±1.02	7.86±1.19	0.72±1.02	3.93±0.59
1	𝟏𝟓.𝟎𝟐±𝟑.𝟎𝟒^∗∗	2.85±2.55	𝟏𝟕.𝟏𝟎±𝟑.𝟓𝟕^∗	2.77±1.02^¤	𝟏𝟕.𝟖𝟏±𝟒.𝟗𝟕^∗
2	𝟐𝟔.𝟐𝟖±𝟒.𝟐𝟖^∗∗	𝟏𝟏.𝟓𝟓±𝟑.𝟏𝟖^∗	𝟐𝟑.𝟏𝟒±𝟑.𝟒𝟔^∗	3.19±2.07	𝟏𝟒.𝟏𝟕±𝟐.𝟗𝟖^∗
3	𝟐𝟎.𝟎𝟑±𝟕.𝟎𝟐^∗	𝟏𝟐.𝟑𝟒±𝟑.𝟖𝟔^∗	16.74±6.24^¤	3.02±1.55	𝟏𝟑.𝟗𝟗±𝟑.𝟒𝟔^∗
Primary culture
Group	CA	AT	AF	CB	CrB
C	1.25±1.77	3.01±1.04	1.14±1.61	0.63±0.88	1.14±1.61
1	5.61±3.43^¤	8.80±3.50^¤	5.79±2.81^¤	0.86±0.75	𝟓.𝟓𝟗±𝟏.𝟕𝟖^∗
2	𝟓.𝟏𝟔±𝟏.𝟎𝟐^∗	4.74±0.43^¤	5.43±1.74^¤	0.42±0.59	𝟒.𝟕𝟒±𝟎.𝟒𝟐^∗
3	3.21±1.01	7.94±2.91^¤	3.48±2.15	2.23±0.38^¤	2.23±0.38
	Ad/Del	EcrS	Aneu	Polip	Gaps
C	7.67±2.01	5.28±2.17	13.81±3.46	0.63±0.88	8.30±1.12
1	𝟑𝟐.𝟓𝟗±𝟕.𝟖𝟐^∗	9.95±4.73	23.66±6.13^¤	3.57±4.29	13.61±5.73
2	𝟐𝟔.𝟑𝟔±𝟎.𝟒𝟒^∗∗	3.63±1.99	38.70±23.83	7.68±4.58^¤	𝟏𝟖.𝟗𝟕±𝟏.𝟔𝟗^∗∗
3	𝟏𝟖.𝟓𝟓±𝟏.𝟒𝟗^∗	5.71±2.53	𝟓𝟐.𝟕𝟐±𝟎.𝟑𝟏^∗	𝟔.𝟒𝟐±𝟐.𝟎𝟏^∗	𝟏𝟑.𝟏𝟏±𝟎.𝟖𝟕^∗

 ^∗𝑃>0.05, ^∗∗𝑃>0.01, and ^¤𝑃≥0.1.
CA: centromere association, AT: association of telomere, AF: acentric fragments, CB: chromosome break, CrB: chromatid break, Ad/Del: addition/deletion, EcrS: early chromatid separation, Aneu: aneuploidy, Polip: polyploidy, and gaps.