Beyond the Limits of Oxygen: Effects of Hypoxia in a Hormone-Independent Prostate Cancer Cell Line

Table 2

IC₅₀ (μM) obtained for PC3 cell line after incubation with doxorubicin, epirubicin, cisplatin, and flutamide at 24, 48, 72, and 96 hours of exposure. 𝑅² is also indicated.

Drug	Time (h)	IC50 (𝜇M)	𝑅^2
Doxorubicin	24; 48; 72; 96	9.31; 1.69; 0.42; 0.71	0.88; 0.94; 0.95; 0.99
Epirubicin	24; 48; 72; 96	10.55; 1.11; 0.57; 0.68	0.95; 0.99; 0.92; 0.97
Cisplatin	24; 48; 72; 96	127.08; 15.31; 18.35; 18.76	0.83; 0.98; 0.99; 0.97
Flutamide	24; 48; 72; 96	66.25; 64.00; 57.99; 37.36	0.97; 0.95; 0.97; 0.98