International Scholarly Research Notices

Research Article

Investigating the Relationship between Serum Level of s-Met (Soluble Hepatic Growth Factor Receptor) and Preeclampsia in the First and Second Trimesters of Pregnancy

Table 2

Sensitivity, specificity, positive predictive value, and negative predictive value of s-Met in the first and second trimesters for mild and severe, as well as early- and late-onset preeclampsia.
PreeclampsiaTrimesterCutoff pointSensitivity
95% CI		Specificity
95% CI		Positive predictive value
95% CI		Negative predictive value
95% CI		Relative risk
95% CI		Likelihood Ratio value
Early onset1st18583%
51%–97%		94%
84%–98%		77%
46%–95%		96%
86%–99%		19.62
4.88–78.84		14.44<0.0001
2nd19577%
46%–95%		94%
84%–99%		77%
46%–95%		94%
84%–99%		13.08
4.19–40.8		13.08<0.0001
Late onset1st25063%
46%–78%		84%
70%–93%		77%
59%–94%		73%
58%–84%		2.82
1.73–4.58		3.97<0.0001
2nd27066%
49%–80%		86%
72%–95%		81%
62%–92%		74%
60%–86%		3.1
2.4–4.8		4.825<0.0001
Mild1st26059%
41%–75%		88%
74%–96%		80%
59%–93%		73%
58%–84%		2.91
1.70–4.74		4.941<0.0001
2nd28062%
44%–79%		89%
75%–96%		80%
59%–93%		76%
62%–87%		3.40
1.99–5.79		5.500<0.0001
Severe1st19588%
63%–98%		92%
82%–98%		79%
54%–94%		96%
86%–99%		15.14
4.8–43.8		11.69<0.0001
2nd20086%
64%–97%		98%
89%–100%		95%
74%–99%		94%
84%–99%		16.11
5.34–48.54		42.00<0.0001