Prevalence and Clinical and Immunoviralogical Profile of Human Immunodeficiency Virus-Hepatitis B Coinfection among Children in an Antiretroviral Therapy Programme in Benue State, Nigeria
Table 2
Clinical, demographic, and laboratory characteristics of HIV-HBV coinfection status groups.
Characteristics
Hepatitis BsAg positive (HIV-HBV dually infected)
Hepatitis BsAg negative
Missing data
P value
Mean age in years ± SD
9.74 ± 4.08
7.34 ± 4.19
0.00
Age group in years
≤5
6
153
0.00
6–10
8
114
11–15
17
97
Total
31
364
Gender
Male
12
193
0.18
Female
19
171
Total
31
364
HBV immunization
None/incomplete
20
309
0.01
Complete
11
55
Total
31
364
Route of HIV acquisitions
MTCT
27
339
0.55
Blood transfusion
1
6
Others (sexual)
0
2
Unknown
3
17
Total
31
364
WHO staging*
1 and 2
21
250
0.91
3 and 4
10
105
Total
31
355
Absolute CD4 count in cells/mm, median (IQR)*
334.00 (182.50–830.50)
560.00 (275.00–916.80)
108
0.11
CD4%*
<15
12
64
0.00
15–25
2
50
>25
6
144
Total
20
258
Log10 viral load, Mean ± SD*
4.26 ± 1.29
4.51 ± 1.17
118
0.33
ALT, Median (IQR)*
30.20 (18.50–50.70)
24.70 (16.65–35.32)
8
0.08
Hepatotoxicity*
Normal
20
270
0.43
Elevated
11
77
Total
31
347
SD: standard deviation. IQR: interquartile range. Data of 9 subjects (HIV-HCV coinfected) were excluded.
