Effect of Polyherbal Mixtures on the Treatment of Diabetes

Table 5

Effect of multiherbal extracts on biochemical parameters in control and STZ-induced diabetic rats.

Groups	SGPT (IU/dL)	SGOT (IU/dL)	ALP (IU/dL)	Total protein (mg/dL)	Triglyceride (mg/dL)	Total cholesterol (mg/dL)
Normal control (2 mL/kg)	122.22±2.54	130.51±3.77	55.99±3.99	8.30±1.87	84.55±2.71	138.6±3.11
Diabetic control (2 mL/kg)	214.33±4.40	250±6.02	90.5±4.53	6.16±1.93	214.15±5.10	253.83±6.16
Glibenclamide (10 mg/kg)	110.66±3.13^∗∗	140.16±4.29^∗∗	46.83±4.29^∗∗	8.16±1.46^∗∗	109.66±3.76^∗∗	124±5.92^∗∗
Mixture 1 (400 mg/kg)	130.00±4.46^∗∗	160.16±3.64^∗∗	51.33±5.45^∗∗	5.83±2.21^∗	130.83±4.82^∗∗	146.16±5.33^∗∗
Mixture 2 (400 mg/kg)	121.16±4.15^∗∗	149.33±5.74^∗∗	49.83±5.74^∗∗	7.66±2.15^∗	121.33±4.31^∗∗	138.5±4.49^∗∗
Mixture 3 (400 mg/kg)	117.00±3.39^∗∗	142.33±5.30^∗∗	47.5±4.66^∗∗	8±2.27^∗∗	112.5±4.79^∗∗	131.16±5.69^∗∗
Mixture 4 (400 mg/kg)	118.5±3.44^∗∗	138.98±3.77^∗∗	40.62±3.65^∗∗	5.66±2.54^∗	118.34±3.56^∗∗	122.44±4.23^∗∗
Mixture 5 (400 mg/kg)	119.33±3.56^∗∗	145±3.87^∗∗	48.4±5.23^∗∗	6.67±4.33^∗	120.5±4.89^∗∗	135.5±4.33^∗∗

Results expressed as mean ± SD (𝑛=6). Treatment was done for 21 days. The data were statistically analysed by one-way ANOVA, followed by Dunnett’s 𝑡-test. ^∗𝑃<0.01, ^∗∗𝑃<0.05. 𝑃 values less than 0.01 were considered more significant.