Fine-Needle Aspiration Cytology Can Play a Role in Neoadjuvant Chemotherapy in Operable Breast Cancer

Table 1

Advantages and disadvantages of FNAC versus CNB.

	FNAC	CNB
General  considerations
Rapid diagnosis	Yes	No
Special experience required	Yes	No
Pain discomfort	Very low	Low
Complication rate	Very low	Low
Diagnostic  performances
Accurate for nonpalpable lesions or microcalcifications	No	Yes
Accurate for palpable lesions or mass with microcalcifications	Yes	Yes
Distinction between in situ and invasive carcinoma	No	Yes
Distinction of low grade lesions (ADH, papilloma, etc.)	Very difficult	Difficult
Unsatisfactory sample	High	Low
Immunohistochemistry	Yes	Yes
In situ hybridisation	Yes	Yes
DNA/RNA isolation for molecular biology	Yes	Yes
Standardization of fixation	Very optimal	Optimal
Tissue/cell bank	Yes	Yes