Research Article

Differential Prognostic Indicators for Locoregional Recurrence, Distant Recurrence, and Death of Breast Cancer

Table 1

Clinical profiles and treatment of breast cancer ( ), by first occurring events.

CharacteristicsRecurrence value
Event-free ( ) Locoregional ( )Distant ( )Death ( )
% % % %

Age (year)
 ≤4516626.12530.13038.5412.90.030
 >4547173.95869.94861.52787.1
Types of surgery
 MRM54385.27286.87089.72683.90.120
 Simple mastectomy406.3910.856.4412.9
 BCS548.522.433.913.2
Pathological tumor size (cm)
 ≤227242.72327.71620.51032.3<0.001
 >236557.36072.36279.52167.7
Histological type
 Ductal carcinoma59092.68298.87798.73096.80.191
 Lobular carcinoma50.800.0000.0000.00
 Other types426.611.211.313.2
Histological grade
 I11019.289.9912.027.40.027
 II28048.94656.83850.7933.3
 III18331.92733.32837.31659.3
Stage
 121834.21619.3911.539.7<0.001
 235355.44351.84152.62271.0
 36610.42428.92835.9619.3
Dissected axillary lymph nodes
 <10 12520.32025.61723.0724.10.641
 ≥1049079.75874.45777.02275.9
Positive axillary lymph nodes
 ≤353086.04253.93851.42069.0<0.001
 >38614.03646.13648.6931.0
LVI
 Absent37760.12329.52229.01136.7<0.001
 Present25039.95570.55471.01963.3
Receptor status
 ER receptor
  Positive39863.64455.03647.42066.70.027
  Negative22836.43645.04052.61033.3
 PR receptor
  Positive35156.04252.53039.51860.00.047
  Negative27644.03847.54660.51240.0
 HER2 receptor
  Positive23640.53854.33549.31139.30.093
  Negative34759.53245.73650.71760.7
Treatment
 Radiotherapy
  Yes19931.34149.45266.7826.7<0.001
  No43668.74250.62633.32273.3
 Hormonal therapy
  Yes41865.64857.83848.72374.20.011
  No21934.43542.24051.3825.8
 Chemotherapy
  Yes54786.38096.47393.61963.3<0.001
  No8713.733.656.41136.7

MRM: modified radical mastectomy; BCS: breast-conserving surgery; LVI: lymphovascular invasion; ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor receptor 2.