Table of Contents
ISRN Biophysics
Volume 2013, Article ID 948074, 7 pages
Research Article

The Skeletal Muscle Impedancemetric Characteristics as a Marker for Detection of Functional State of Organism

1Department of Biomedical Engineering, UNESCO Chair-Life Sciences International Postgraduate Educational Center, 31 Acharyan Street, 0040 Yerevan, Armenia
2Department of ECE, University of Colorado Boulder, 80309-0425 Colorado, USA

Received 12 February 2013; Accepted 6 March 2013

Academic Editors: S. Dasdag and M. P. Ponomarenko

Copyright © 2013 Anush Deghoyan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Previously it has been shown that cell hydration is a universal and extrasensitive marker for different environmental mediums and functional state of tissue and organism. The comparative study of cell hydration of different organs (brain cortex, liver, and skeletal muscle) at various experimental conditions (microstress, pathology, and different poisons) was realized. It was shown that among tissues of different organs muscle hydration is more sensitive to any change of functional state of organism and environmental medium. The study of correlation between tissue muscle hydration and double-frequency measurement impedance method indicated that the differences between muscle reactive conductivity measured at high frequency (HF) and low frequency (LF) could be an adequate marker for detection of muscle hydration. The animal poisoning, stress, and pathology-induced tissue hydration were accompanied by increase in . The observed close correlation between time-dependent tissue hydration and in different environmental mediums can be a marker for detection of postmortal period as well as for characterizing environmental medium of the corpse.