The Cooling Effect on Proinflammatory Cytokines Interferon-Gamma, Tumor Necrosis Factor-Alpha, and Nitric Oxide in Patients with Multiple Sclerosis

Table 3

Pre- and postcooling values of nitric oxide, TNF-𝛼, and IFN-𝛾.

	Pre-	Post-	Difference	95% CI	𝑃
NO	10,96±10,4	6,33±7,9	4,63±7,4	1,17–8,11	0,002
TNF-𝛼	6,04±4,4	5,33±3,2	0,71±2,6	0,52–1,94	0,33
IFN-𝛾	11,01±26,4	9,25±11,2	1,76±7,23	1,64–5,16	0,46

Values are expressed as mean ± SD. Difference: Post: Precooling difference.